Depression is a condition that causes intense feelings of sadness, hopelessness, and personal emptiness. It can be brought on by stress, regret, trauma, loss, or even a genetic predisposition to developing the disorder. People who are suffering from depression often present with chronic fatigue or appetite changes. They may also experience social withdrawal, loss of motivation, and loss of interest in activities. Fortunately, mental health care is available to help people who suffer from depression.